Comprehensive Medicinal Chemistry III


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Comprehensive Medicinal Chemistry III	Kontakt/Bestellung Contact/Order via E-Mail: info@digento.de
3rd Edition Hrsg. v. Samuel Chackalamannil, David Rotella und Simon Ward
Online
Inhalt :: Content Umfassendes Referenzwerk mit über 280 Überblicksartikeln zum aktuellen Forschungsstand und zu den neuesten Entwicklungen der medizinischen Chemie und ihrer Anwendungsbereiche. Zu den behandelten Themenbereichen zählen u.a. Drug Targeting, biomolekulare Therapeutika, Entwicklung von bio-chemischen Tools, Datenerfassung und -analyse, in silico-Modelle als Prädiktoren für biologische Eigenschaften, Identifikation und Validierung neuer Zielmoleküle, Ansätze zur Quantifizierung des Target-Engagements, neue Methoden zur Synthese von Wirkstoffkandidaten wie Grüne Chemie oder Entwicklung von neuartigen Gerüst- oder Bindesubstanzen für die Wirkstoffforschung sowie die Rolle der Zulassungsbehörden in der Wirkstoffforschung. Der Online-Ausgabe liegt die 2017 erschienene 8-bändige Printausgabe zugrunde. Das Werk ergänzt und erweitert "Comprehensive Medicinal Chemistry" (1990) und "Comprehensive Medicinal Chemistry" (2007).
Verlag :: Publisher Elsevier Science
Preis :: Price Preise auf Anfrage / Prices on request
Das Angebot richtet sich nicht an Verbraucher i. S. d. § 13 BGB und Letztverbraucher i. S. d. PAngV.
ISBN/ISSN 978-0-12-803201-5 Bestellnummer bei digento :: digento order number 10226069
Verlagsinformation :: Publisher's information Comprehensive Medicinal Chemistry III, Third Edition provides a contemporary and forward looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Key Features Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs Readership Graduate and postgraduate drug discovery scientists in research organizations engaged in the discipline, primarily but not exclusively medicinal chemists. Computational chemists, therapeutic area biologists and pharmacologists, ADME scientists as well as process chemists. A medicinal chemist at any point in his/her career who desires an up-to-date source of information on not only the latest trends in the discipline, but also specifics on the newest information in a particular field such as biologics and specific discovery targets such as kinase inhibitors in cancer.
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