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The Cochrane Library

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via E-Mail:
info@digento.de  Contact/Order: info@digento.de

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Inhalt :: Content

Die Cochrane Library ist die umfangreichste Datensammlung zur evidenzbasierten Medizin weltweit. Sie beinhaltet rund 700.000 Eintragungen bzw. Reviews von Zeitschriften, Konferenzberichten und anderen Quellen zu den neuesten, nachgewiesenen medizinischen Behandlungen sowie zu kontrollierten klinischen Studien. Die Cochrane Library umfasst folgende Teildatenbanken:

  • Cochrane Database of Systematic Reviews (CDSR)
  • Database of Abstract of Reviews of Effects (DARE)
  • Cochraine Central Register of Contolled Trials (CENTRAL)
  • Cochrane Methodology Register (CMR)
  • Health Technology Assessment Database (HTA)
  • NHS Economic Evaluation Database (NHSEED)

Jährlicher Zuwachs. ca. 30.000 Eintragungen. Updates: vierteljährlich.

The Cochrane Library

Verlag :: Publisher

John Wiley & Sons

Preis :: Price

Preise auf Anfrage / Prices on request

Das Angebot richtet sich nicht an Verbraucher i. S. d. § 13 BGB und Letztverbraucher i. S. d. PAngV.

Bestellnummer bei digento :: digento order number

103133

Verlagsinformation :: Publisher's information

The Cochrane Library is a collection of high quality, evidence-based healthcare databases that enables users to make informed choices about diagnostic and treatment options. It is designed to inform people providing and receiving care, as well as those responsible for research, teaching, funding and administration at all levels.

The Cochrane Library provides systematically derived, reliable indications as to whether or not a particular treatment or intervention is more effective than another, considering both benefits and side effects.

The databases and the current numbers of records are:

The Cochrane Database of Systematic Reviews (CDSR)

A systematic review identifies an intervention for a specific disease or other problem in health care, and determines whether or not this intervention works. To do this authors locate, appraise and synthesise evidence from as many relevant scientific studies as possible. They summarise conclusions about effectiveness, and provide a unique collation of the known evidence on a given topic, so that others can easily review the primary studies for any intervention.

Systematic reviews differ from other types of review in that they adhere to a strict design in order to make them more comprehensive, thus minimising the chance of bias, and ensuring their reliability. Rather than reflecting the views of the authors, or being based on a partial selection of the literature, (as is the case with many articles and reviews that are not explicitly systematic), they contain all known references to trials on a particular intervention and a comprehensive summary of the available evidence. The reviews are therefore also valuable sources of information for those receiving care, as well as for decision makers and researchers.

The Cochrane Database of Methodology Reviews (CDMR)

The CDMR contains two types of document: cochrane methodology reviews and protocols. Cochrane Methodology Reviews are full-text systematic reviews of methodological studies. The reviews are both highly structured and systematic. Evidence from methodological research is included or excluded on the basis of explicit quality criteria, thus minimising bias. Each review covers a specific and well-defined area of methodology. Data from studies are often combined statistically to increase the power of the findings of numerous studies, which on their own may be too small to produce reliable results. In such cases, the review may also include graphs presenting the data from each individual study. Protocols provide place-markers for reviews, which are currently being written. They summarise the background and the rationale of the review.

The Cochrane Central Register of Controlled Trials (CENTRAL)

CENTRAL includes details of published articles taken from bibliographic databases (notably MEDLINE and EMBASE), and other published and unpublished sources. CENTRAL records include the title of the article, information on where it was published (bibliographic details) and, in many cases, a summary of the article. They do not contain the full text of the article.

About three-fifths of the records in CENTRAL are taken from MEDLINE. In addition, each Collaborative Review Group maintains and updates a collection of controlled trials relevant to its own area of interest, these are called "Specialised Registers"

Each group may also collect items which are not relevant to its own field of interest; these are known as "Handsearch Results". The registers and handsearch results are assembled and collated by the US Cochrane Center before incorporation into The Cochrane Library.

The Database of Abstracts of Reviews of Effects (DARE)

A systematic review identifies an intervention for a specific disease or other problem in health care, and determines whether or not this intervention works. To do this authors locate, appraise and synthesise evidence from as many relevant scientific studies as possible. They summarise conclusions about effectiveness, and provide a unique collation of the known evidence on a given topic, so that others can easily review the primary studies for any intervention.

Systematic reviews differ from other types of review in that they adhere to a strict design in order to make them more comprehensive, thus minimising the chance of bias, and ensuring their reliability. Rather than reflecting the views of the authors, or being based on a partial selection of the literature (as is the case with many articles and reviews that are not explicitly systematic), they contain all known references to trials on a particular intervention and a comprehensive summary of the available evidence. The reviews are therefore valuable sources of information for those receiving care, as well as for decision makers and researchers.

DARE is produced by the NHS Centre for Reviews and Dissemination (NHS CRD) at the University of York, UK.

The NHS Centre for Reviews and Dissemination (NHS CRD) was established in January 1994 to provide the NHS with information on the effectiveness of treatments, and on the delivery and organisation of health care. CRD staff write systematic reviews on selected topics, develop a database of high-quality reviews, and provide an information service.

The Health Technology Assessment Database (HTA)

This database contains information on healthcare technology assessments, (defined as prevention and rehabilitation, vaccines, pharmaceuticals and devices, medical and surgical procedures and the systems within which health is protected and maintained). The database contains details of ongoing projects and completed publications from health technology assessment organisations. HTA records follow a standard structure. Some records contain the title of the project, with the name of the centre responsible and an indication of where further details can be obtained, (usually including both a postal address and a website). Other records contain publication details, with structured abstracts where available. Records do not, in either case, contain the full text of the report.

The HTA database is produced by the NHS Centre for Reviews and Dissemination (NHS CRD) at the University of York, UK, using information obtained from members of INAHTA and other health technology assessment organisations.

The NHS Economic Evaluation Database (NHS EED)

This database contains structured abstracts of articles describing economic evaluations of health care interventions. The articles are identified by searching through key medical journals, bibliographic databases and less widely-available literature. A paper will be included if it provides a comparison of treatments and examines both the costs and outcomes of the alternatives. The quality of the database contents is controlled by ensuring that all reviewers work to specified guidelines, and that independent checks on the review process are carried out. The database also includes bibliographic details of articles examining relevant topics, (for example the burden of illness, economic methodology papers, and reviews of economic evaluations), and short abstracts of studies originally included in the Department of Health Register of Cost-Effective Studies. Records do not contain the full text of the original article.

Full economic evaluations, as defined by the NHS CRD, can be one of the following:

  • a cost-benefit analysis (CBA), which measures both costs and benefits in monetary values and calculates net monetary gains or losses (presented as a cost-benefit ratio);
  • a cost-effectiveness analysis (CEA), which compares interventions with a common outcome (such as blood pressure level) to discover which produces the maximum outcome for the same input of resources in a given population;
  • a cost-utility analysis (CUA), which measures the benefits of alternative treatments or types of care by using clearly defined utility measures (such as quality-adjusted life years).

NHS EED is produced by the NHS Centre for Reviews and Dissemination (NHS CRD) at the University of York, UK.

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